Leptin Supplements: 10 Best Supplements Available in the Market Today

leptin supplements

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We all dream of having the perfect body, but most of us are tired of trying endless diets, exercise routines, and various lifestyle changes that make us miserable and amount to nothing. Some of us even become convinced losing weight isn’t in the cards for us due to our many tries and fails. What we need to realize is that anyone and everyone can lose weight and get the body of their dreams by committing to a healthier life that includes taking leptin supplements. Most people overlook supplements as a way to lose weight, but could this be the answer we’ve all been waiting for?

Leptin Supplements: FAQ

1. What Is Leptin?

Leptin is best described as a protein hormone that is derived from fat cells. It’s responsible for regulating hunger and letting the brain know when your stomach is filled up. Discovered back in 1994, leptin has been named as one of the most important hormones responsible for the regulation of one’s body weight. It also plays a key role in controlling fat levels in the body and increasing one’s metabolism.

When people fall into the overweight category, it’s usually because the level of leptin in their bodies is insufficient and does not inform the brain properly as to when the stomach is full. There is also a condition called leptin resistance, which means the body has levels of leptin that are too high and do not work efficiently. This aids in excess fat being stored in the bodies of those with resistance, leading to obesity.

2. Overall Price Range?

As with most consumer products, the price range will depend on the individual customer’s needs, uses, and budget. Leptin supplements have a narrower price range than other items, but it can be hard to distinguish which brands are reputable and which aren’t. For our top ten list, we only included items we feel are the best value for the money and have the greatest potency (and therefore the best results) out there on the market. The overall price range for our top ten list is $12 to $40.

How We Reviewed

Our team of experts has spent much time and effort researching and testing out different varieties of leptin supplements until they were able to compile a list of the ten best supplements on the market. We reviewed these items based on the following parameters: their features, their pros and cons, their price, and where to buy them.

What We Reviewed

  • NatureWise CLA 1250
  • CLA 1250 (High Potency) 180 Veggie Softgel Capsules
  • NatureGenX – Leptin Burn
  • BulkSupplements CLA Softgels
  • Havasu Nutrition Extra Strength DHEA 50 mg Supplement
  • BRI L-Carnitine – 1000mg
  • Puritans Pride Super Strength Myo-leptin Cla 1500 Mg
  • CLA Safflower Oil
  • Sheer SHRED PM, Nighttime Fat Burner and Sleep Aid Supplement
  • African Mango Natural Weight Loss Formula

[amazon link=”B00OTSF7L6″ title=”NatureWise CLA 1250″ /]

[amazon box=”B00OTSF7L6″]


This is one of the best leptin supplements because it’s been known to help people lower their body mass as well as speed up the weight-losing process. CLA, here, stands for conjugated linoleic acid and helps reduce leptin levels while increasing the sensitivity of leptin’s signals to the brain. This supplement is high in potency, is natural and non-stimulating, contains no artificial ingredients, no gluten, and is GMO-free. Each of the 180 soft gels contains 1,000 mg of active CLA and these pills are derived from safe, reliable, non-GMO safflower oil with a high potency of 80%.

[amazon link=”B00IQFMZRC” title=”CLA 1250 (High Potency) 180 Veggie Softgel Capsules” /]

[amazon box=”B00IQFMZRC”]


These leptin supplements are, as the name implies, high potency and contain 80% CLA per soft gel. Each tablet contains a whopping 1250 mg of CLA which is one of the most potent items on our list. These supplements offer natural weight-loss as you stay dedicated to consistently taking their veggie soft gels that contain no stimulants in the formula. These supplements also have the benefit of being a great source of omega-6 fatty acids.

[amazon link=”B077TX6QSB” title=”NatureGenX – Leptin Burn” /]

[amazon box=”B077TX6QSB”]


These leptin supplements will benefit everyone as they are made to work well for both men and women. These help control one’s appetite even for busy people who have full lives and are always on the go. This formula is completely stimulant-free and is clinically proven to promote weight loss by making the user feel full for a longer time after a light meal. Always consult your doctor or medical provider before taking these supplements and be sure to take them with a full glass of water. You should also expect to formulate a plan for getting ample nutrition and even exercising if you want these supplements to have maximum benefits.

[amazon link=”B00HAS5BUY” title=”BulkSupplements CLA Softgels” /]

[amazon box=”B00HAS5BUY”]


These leptin supplements come to us from a brand that’s well known in the supplement industry. They pride themselves on selling and manufacturing only the most clean-cut and potent products that see results, results, and more results. BulkSupplements only uses the most natural ingredients and never has any fillers in their formula. When you take these tablets, you’ll experience a boosted immune system and a boosted metabolic rate. This brand makes sure to test their products in labs before allowing them to be sold to the public, so you know you’re getting quality ingredients.

[amazon link=”B01K2GYI04″ title=”Havasu Nutrition Extra Strength DHEA 50 mg Supplement” /]

[amazon box=”B01K2GYI04″]


These leptin supplements focus on the hormones of the user and regulating them. Sometimes, when you experience hormonal imbalances, your life feels like it’s crashing down around you, and this can lead to insufficient or overbearing leptin levels in the body. Luckily for those of us who deal with hormonal issues, the Havasu Nutrition brand is here to help us. These leptin hormone supplements will not only support weight loss efforts, but they will also keep your hormones properly balanced, which will make you feel much better about your life and surroundings.

[amazon link=”B00RUURR9U” title=”BRI L-Carnitine – 1000mg” /]

[amazon box=”B00RUURR9U”]


These small, easy-to-swallow tablets each contain 1,000 mg of L-carnitine, which is a protein that’s often found in body-building supplements. It has balancing capabilities for leptin and will make it easier for you to regulate what you eat. Keep in mind, however, that the only active ingredient in these tablets is the L-carnitine, so it’s recommended you purchase additional leptin supplements along with it. There are absolutely no stimulants added to this supplement and no counter-interacting herbs either.

[amazon link=”B0097AIH4U” title=”Puritans Pride Super Strength Myo-leptin Cla 1500 Mg” /]

[amazon box=”B0097AIH4U”]


These leptin supplements come to us from a well-known, trusted, and revered brand that’s used and recommended by consumers and medical professionals near and far. This company has been manufacturing quality supplement products for years, and when you buy from Puritans Pride, you can rest assured you’re getting a product that’s been thoroughly tested for its quality and potency. They stand behind their supplement through thick and thin. They’re so sure you’ll love their products, they offer a 60-day money-back guarantee if you don’t totally love them or see no results.

[amazon link=”B00L2JSOYM” title=”CLA Safflower Oil” /]

[amazon box=”B00L2JSOYM”]


These leptin supplements have a no-nonsense formula that contains only what you need and none of what you don’t. These tablets each contain a whopping 3,000 mg of CLA derived from safflower. Your results may vary based on how your body interacts with the ingredients, but the presence of safflower oil makes these supplements a great resource for boosting one’s metabolism. These are stimulant-free, non-GMO, gluten-free, and manufactured right here in the US.

[amazon link=”B079NQDCQW” title=”Sheer SHRED PM, Nighttime Fat Burner and Sleep Aid Supplement” /]

[amazon box=”B079NQDCQW”]


These leptin supplements focus more on assisting with nightly rest as well as losing weight and curbing the appetite. This brand of leptin supplements contains melatonin and is meant to be taken on a nightly basis. For those who have messed up sleep schedules that could be affecting their leptin levels, these are the perfect solution. This supplement also contains an herb called ginkgo biloba, which has been known to be very effective in increasing focus. If this is something that you already struggle with, the Sheer SHRED PM supplement is the answer to your prayers!

[amazon link=”B01861PWZC” title=”African Mango Natural Weight Loss Formula” /]

[amazon box=”B01861PWZC”]


These leptin supplements have fat-burning and appetite suppressant properties that will help you lose weight over time in a safe and reliable way. It’s been shown in recent years that African mango extract helps with weight loss, but this product fails to specify how many mg it contains per tablet or per bottle. You should also be aware that this supplement contains some caffeine in the form of green coffee bean extracts and green tea extracts. While these will curb the appetite and assist in weight loss, they may also make some people feel as though they’ve just had a massive cup of coffee.

Note: consult with your healthcare provider if you have high blood pressure before taking this supplement.


[amazon box=”B00OTSF7L6, B00IQFMZRC, B077TX6QSB, B00HAS5BUY, B01K2GYI04, B00RUURR9U, B0097AIH4U, B00L2JSOYM, B079NQDCQW, B01861PWZC,” template=”table”]

The Verdict

We hope our list of the ten best leptin supplements has given you a few good ideas for helping yourself achieve the body of your dreams. If an unusual sleeping schedule is the main cause of your weight problems, we highly recommend the Sheer SHRED PM, Night time Fat Burner, and Sleep Aid Supplement model. This model also contains herbs that help with focusing if you also have troubles in that department. If you’re looking for a no-nonsense formula that contains only the ingredients you want with no stimulants, GMOs, gluten, or any of the like, we recommend going with the CLA Safflower Oil model.

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